Overview

  • Product name
  • Description
    Mouse polyclonal to DGKZ
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length DGKZ protein (Human)

  • Positive control
    • DGKZ transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab67791 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 135 kDa (predicted molecular weight: 124 kDa).

Target

  • Function
    Displays a strong preference for 1,2-diacylglycerols over 1,3-diacylglycerols, but lacks substrate specificity among molecular species of long chain diacylglycerols. Isoform 2 but not isoform 1 regulates RASGRP1 activity.
  • Tissue specificity
    Highest levels in brain, and substantial levels in skeletal muscle, heart, and pancreas. Isoform 1 is predominantly expressed in muscle.
  • Sequence similarities
    Belongs to the eukaryotic diacylglycerol kinase family.
    Contains 2 ANK repeats.
    Contains 1 DAGKc domain.
    Contains 2 phorbol-ester/DAG-type zinc fingers.
  • Post-translational
    modifications
    Phosphorylation of the MARCKS homology domain by PKC reduces nuclear accumulation of DGK-zeta.
  • Cellular localization
    Cytoplasm. Nucleus. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • DAG kinase zeta antibody
    • DAGK5 antibody
    • DAGK5 PEN antibody
    • DAGK6 antibody
    • DGK ZETA antibody
    • DGK-zeta antibody
    • Dgkz antibody
    • DGKZ_HUMAN antibody
    • Diacylglycerol kinase zeta antibody
    • Diglyceride kinase zeta antibody
    • hDGKzeta antibody
    see all

Images

  • All lanes : Anti-DGKZ antibody (ab67791) at 1/500 dilution

    Lane 1 : DGKZ transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 124 kDa
    Observed band size : 135 kDa (why is the actual band size different from the predicted?)

References

ab67791 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab67791.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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