The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 34 kDa (predicted molecular weight: 34 kDa).
FunctionCatalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.
Tissue specificityWidely expressed with highest levels found in heart, placenta, lung, liver, kidney, pancreas, thyroid, testis, stomach, trachea and spinal cord. Lower levels found in skeletal muscle, intestine and lymph node. No expression detected in brain. In the retina, expressed in cone but not rod outer segments.
Sequence similaritiesBelongs to the short-chain dehydrogenases/reductases (SDR) family.