Overview

  • Product name
  • Description
    Mouse polyclonal to DHRS4
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-278 of Human DHRS4

  • Positive control
    • Human liver, transfected 293T cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: Whole serum
  • Purity
    Whole antiserum
  • Clonality
    Polyclonal
  • Isotype
    IgG

Applications

Our Abpromise guarantee covers the use of ab68095 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 27 kDa (predicted molecular weight: 27 kDa).

Target

  • Function
    Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones.
  • Tissue specificity
    Isoform 1 is predominantly expressed in normal cervix (at protein level). Isoform 4 is expressed in some neoplastic cervical tissues, but not in normal cervix (at protein level). Isoform 5 and isoform 6 are expressed in a few neoplastic cervical tissues.
  • Sequence similarities
    Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • Cellular localization
    Peroxisome. Isoform 1 is peroxisomal, while isoform 4 is not.
  • Information by UniProt
  • Database links
  • Alternative names
    • AI043103 antibody
    • AI790593 antibody
    • Carbonyl reductase antibody
    • CR antibody
    • D14Ucla2 antibody
    • Dehydrogenase/reductase SDR family member 4 antibody
    • Dhrs4 antibody
    • DHRS4_HUMAN antibody
    • humNRDR antibody
    • mouNRDR antibody
    • NADPH dependent carbonyl reductase/NADP retinol dehydrogenase antibody
    • NADPH dependent retinol dehydrogenase/reductase antibody
    • NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase antibody
    • NADPH-dependent retinol dehydrogenase/reductase antibody
    • NDRD antibody
    • NRDR antibody
    • Peroxisomal short chain alcohol dehydrogenase antibody
    • Peroxisomal short-chain alcohol dehydrogenase antibody
    • PHCR antibody
    • PRO1800 antibody
    • PSCD antibody
    • RRD antibody
    • SCAD-SRL antibody
    • SCADSRL antibody
    • Short chain dehydrogenase/reductase family member 4 antibody
    • Short-chain dehydrogenase/reductase family member 4 antibody
    • UNQ851 antibody
    see all

Anti-DHRS4 antibody images

  • Anti-DHRS4 antibody (ab68095) at 1/500 dilution + human liver at 25 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 27 kDa
    Observed band size : 27 kDa
  • All lanes : Anti-DHRS4 antibody (ab68095) at 1/500 dilution

    Lane 1 : DHRS4 transfected 293T cell lysate
    Lane 2 : non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 27 kDa
    Observed band size : 27 kDa
    Additional bands at : 26 kDa. We are unsure as to the identity of these extra bands.

References for Anti-DHRS4 antibody (ab68095)

This product has been referenced in:
  • Admoni-Elisha L  et al. Novel Biomarker Proteins in Chronic Lymphocytic Leukemia: Impact on Diagnosis, Prognosis and Treatment. PLoS One 11:e0148500 (2016). Human . Read more (PubMed: 27078856) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab68095.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up