• Product nameAnti-DHX58 antibody
    See all DHX58 primary antibodies
  • Description
    Rabbit polyclonal to DHX58
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Orangutan
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Mouse DHX58.

  • Positive control
    • This antibody gave a positive signal in MCF7 whole cell lysate.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferpH: 7.40
    Preservative: 0.02% Sodium azide
    Constituent: PBS
    Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab100882 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 77 kDa (predicted molecular weight: 77 kDa).


  • FunctionParticipates in innate immune defense against viruses. Upon interaction with intracellular dsRNA produced during viral replication, triggers a transduction cascade which results in the induction and expression of antiviral cytokines such as IFN-beta and RANTES (CCL5). The RNA helicase domain may recognize and structurally modify viral RNA to facilitate detection by DDX58/RIG-I or by IFIH1/MDA5 whose affinity for dsRNA is lower.
  • Sequence similaritiesBelongs to the helicase family.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • D11LGP2 antibody
    • D11lgp2e antibody
    • DEXH (Asp Glu X His) box polypeptide 58 antibody
    • DEXH box polypeptide 58 antibody
    • DHX 58 antibody
    • DHX58 antibody
    • DHX58_HUMAN antibody
    • LGP 2 antibody
    • LGP2 antibody
    • Ortholog of mouse D11lgp2 antibody
    • Probable ATP dependent helicase LGP2 antibody
    • Probable ATP dependent RNA helicase DHX58 antibody
    • Probable ATP-dependent helicase LGP2 antibody
    • Probable ATP-dependent RNA helicase DHX58 antibody
    • Protein D11Lgp2 homolog antibody
    • RIG-I-like receptor LGP2 antibody
    • RLR antibody
    • RNA helicase LGP2 antibody
    see all

Anti-DHX58 antibody images

  • Anti-DHX58 antibody (ab100882) at 1 µg/ml + MCF7 (Human breast adenocarcinoma cell line) Whole Cell Lysate at 10 µg

    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 77 kDa
    Observed band size : 77 kDa

    Exposure time : 12 minutes

References for Anti-DHX58 antibody (ab100882)

ab100882 has not yet been referenced specifically in any publications.

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