Overview

  • Product name
  • Description
    Rabbit polyclonal to DHX58
  • Tested applications
    Suitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to 15 aa near the C-terminus of Human DHX58.

Properties

Applications

Our Abpromise guarantee covers the use of ab112546 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 77 kDa.
IP 1/200.

Target

  • Function
    Participates in innate immune defense against viruses. Upon interaction with intracellular dsRNA produced during viral replication, triggers a transduction cascade which results in the induction and expression of antiviral cytokines such as IFN-beta and RANTES (CCL5). The RNA helicase domain may recognize and structurally modify viral RNA to facilitate detection by DDX58/RIG-I or by IFIH1/MDA5 whose affinity for dsRNA is lower.
  • Sequence similarities
    Belongs to the helicase family.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • D11LGP2 antibody
    • D11lgp2e antibody
    • DEXH (Asp Glu X His) box polypeptide 58 antibody
    • DEXH box polypeptide 58 antibody
    • DHX 58 antibody
    • DHX58 antibody
    • DHX58_HUMAN antibody
    • LGP 2 antibody
    • LGP2 antibody
    • Ortholog of mouse D11lgp2 antibody
    • Probable ATP dependent helicase LGP2 antibody
    • Probable ATP dependent RNA helicase DHX58 antibody
    • Probable ATP-dependent helicase LGP2 antibody
    • Probable ATP-dependent RNA helicase DHX58 antibody
    • Protein D11Lgp2 homolog antibody
    • RIG-I-like receptor LGP2 antibody
    • RLR antibody
    • RNA helicase LGP2 antibody
    see all

References

ab112546 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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