Overview

  • Product nameAnti-Digitoxin antibody
  • Description
    Rabbit polyclonal to Digitoxin
  • Specificity%Cross-Reactivity (determined by RIA): Cortisol <0.5 Digitoxin <3 17-Estradiol <0.5 Progesterone <0.5 Testosterone <0.5
  • Tested applicationsSuitable for: RIAmore details
  • Immunogen

    Digoxin-BSA.

Properties

Applications

Our Abpromise guarantee covers the use of ab50318 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
RIA
  • Application notesRIA: 1/10000. Dilute the antiserum in 0.01M phosphate buffered saline, pH 7.4, containing 0.1% sodium azide. RIA Affinity Constant: Ka =3 x 109 - 1 x 1010 L/mole (as determined by a Scatchard plot using RIA).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceDigitoxin is a purified cardiac glycoside similar in structure and function to Digoxin. Unlike Digoxin, Digitoxin is eliminated from the body via the liver and not the kidneys. Both drugs are used to treat various heart conditions. Cardiac glycosides bind to a site on the extracellular aspect of the a-subunit of the Na+/K+ ATPase pump in the membranes of heart cells (myocytes). This causes an increase in the level of sodium ions in the myocytes, which then leads to a rise in the level of calcium ions.

    References for Anti-Digitoxin antibody (ab50318)

    ab50318 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab50318.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"