Overview

  • Product name
    Dimaprit dihydrochloride
  • Description
    Selective H2 agonist
  • Biological description
    Selective H2 agonist. Some selectivity for H3. Does not readily cross the blood-brain barrier. Systemically active following oral administration.
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Liu C  et al. Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow. Mol Pharmacol 59:420-6 (2001). Read more (PubMed: 11179434) »
  • van der Goot H & Timmerman H Selective ligands as tools to study histamine receptors. Eur J Med Chem 35:5-20 (2000). Read more (PubMed: 10733599) »
  • Nakamura T  et al. Efficacy of a selective histamine H2 receptor agonist, dimaprit, in experimental models of endotoxin shock and hepatitis in mice. Eur J Pharmacol 322:83-9 (1997). Read more (PubMed: 9088875) »
  • Coruzzi G  et al. Cardiovascular effects of the novel histamine H2 receptor agonist amthamine: interaction with the adrenergic system. Naunyn Schmiedebergs Arch Pharmacol 353:417-22 (1996). Read more (PubMed: 8935708) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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