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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer Preservative: None
Constituents: 1X PBS, pH 7.2
Concentration information loading...
Purity Protein G purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa).
Function Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.
Sequence similarities Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Cellular localization Nucleus > nucleolus.
Information by UniProt
18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase antibody
18S rRNA dimethylase antibody
Anti-DIMT1L antibody images
References for Anti-DIMT1L antibody (ab69434)
This product has been referenced in:
et al. The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis. Mol Biol Cell 26:2080-95 (2015).
Read more (PubMed: 25851604) »
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for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"