Anti-Dio3 antibody (ab102926)


  • Product nameAnti-Dio3 antibody
    See all Dio3 primary antibodies
  • Description
    Rabbit polyclonal to Dio3
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within the C terminal amino acids 249-278 of Human Dio3 (NP_001353).

  • Positive control
    • HepG2 cell line lysates. Human hepatocarcinoma tissue.



Our Abpromise guarantee covers the use of ab102926 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 34 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.


  • FunctionResponsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.
  • Tissue specificityExpressed in placenta and several fetal tissues.
  • Sequence similaritiesBelongs to the iodothyronine deiodinase family.
  • Cellular localizationCell membrane. Endosome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5DIII antibody
    • D3 antibody
    • Deiodinase iodothyronine type 3 antibody
    • Deiodinase iodothyronine type III antibody
    • Dio 3 antibody
    • Dio3 antibody
    • DIOIII antibody
    • IOD3_HUMAN antibody
    • Iodothyronine deiodinase placental type antibody
    • MGC124117 antibody
    • MGC124118 antibody
    • Thyroxine deiodinase type III antibody
    • Thyroxine deiodinase type III (selenoprotein) antibody
    • TXDI3 antibody
    • Type 3 DI antibody
    • Type 3 iodothyronine selenodeiodinase antibody
    • Type III 5' deiodinase antibody
    • Type III iodothyronine deiodinase antibody
    • Type-III 5''-deiodinase antibody
    see all

Anti-Dio3 antibody images

  • Anti-Dio3 antibody (ab102926) at 1/100 dilution + HepG2 cell line lysate at 35 µg

    Predicted band size : 34 kDa
  • ab102926 at 1/50 staining Dio3 in Formalin-fixed and paraffin-embedded Human hepatocarcinoma by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Detection utilised DAB.

References for Anti-Dio3 antibody (ab102926)

ab102926 has not yet been referenced specifically in any publications.

Product Wall

Application Immunocytochemistry/ Immunofluorescence
Sample Cow Cell (aortic endothelial cells)
Permeabilization Yes - Saponin 0,1%
Specification aortic endothelial cells
Blocking step PBS/Saponin 0,1%/BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
Fixative PFA 4%

Abcam user community

Verified customer

Submitted Jul 08 2015

Application Western blot
Loading amount 20 µg
Gel Running Conditions Reduced Denaturing
Sample Mouse Tissue lysate - other (Heart)
Specification Heart
Blocking step Super Blocking Buffer as blocking agent for 30 minute(s) · Concentration: 10% · Temperature: 25°C

Abcam user community

Verified customer

Submitted Jul 30 2014

Thank you for your patience. My colleague has been able to add the following peptides to our catalog:

Ab77481 corresponding peptide Ab131396

Ab102926 corresponding peptide Ab131397

Ab22835 corresponding peptide AB131398 ...

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Thank you for your reply.

I will be working on adding these peptides to our catalog, and it may take a couple of days.

Regardingthe TSH beta antibody ab80784, the immunogen was purified human TSH beta. We don't have the beta subuni...

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Thank you for your enquiry.

I have checked our catalog and unfortunately we do not have a blocking peptide for use withab102926.

I'm sorry I could not be more helpful at this time. Please contact me again if you have any further que...

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