Overview

  • Product name
    Diphenhydramine hydrochloride
  • Description
    Potent H1 antagonist
  • Alternative names
    • DPA
  • Biological description
    Potent H1 receptor antagonist (Ki = 1 nM). Shows antihistaminergic, antiemetic, sedative and hypnotic effects.
  • Purity
    > 99%

Properties

References

This product has been referenced in:
  • Parsons ME & Ganellin CR Histamine and its receptors. Br J Pharmacol 147 Suppl 1:S127-35 (2006). Read more (PubMed: 16402096) »
  • Au-Yeung SC  et al. A pharmacokinetic study of diphenhydramine transport across the blood-brain barrier in adult sheep: potential involvement of a carrier-mediated mechanism. Drug Metab Dispos 34:955-60 (2006). Read more (PubMed: 16510542) »
  • Liu H & Farley JM Effects of first and second generation antihistamines on muscarinic induced mucus gland cell ion transport. BMC Pharmacol 5:8 (2005). Read more (PubMed: 15790419) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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