Overview

  • Product nameAnti-Diphtheria Toxin antibody [11D9]
    See all Diphtheria Toxin primary antibodies
  • Description
    Mouse monoclonal [11D9] to Diphtheria Toxin
  • Specificityab53827 reacts primarily with Diphtheria toxin with a low cross reactivity with Diphtheria toxoid (formaldehyde-inactivated Diphtheria toxin).
  • Tested applicationsSuitable for: WB, ELISA, Conjugationmore details
  • Immunogen

    Diphtheria toxoid (formaldehyde inactivated Diphtheria toxin).

  • General notes

    For a recombinant antibody to Diphtheria Toxin, please see - Ab209329

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 0.5M Sodium chloride, 0.01M PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • Clone number11D9
  • IsotypeIgG1
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab53827 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Detects a band of approximately 63 kDa (predicted molecular weight: 58 kDa). 63kDa band corresponds to the proenzyme.
ELISA Use at an assay dependent dilution.
Conjugation Use at an assay dependent dilution.

Target

  • RelevanceCorynebacterium diphtheriae is a gram-positive, nonmotile bacteria found in soil and animal feces. C. diphteriae infect the epithelial cells of the upper respiratory tract from where they produce and secrete a potent toxin. This toxin is absorbed and disseminated through lymph channels and blood to the susceptible tissues of the body.
  • Cellular localizationSecreted
  • Alternative names
    • Corynebacterium diphtheriae toxoid antibody
    • Diphtheria Toxin antibody
    • tox antibody

References for Anti-Diphtheria Toxin antibody [11D9] (ab53827)

This product has been referenced in:
  • Jalah R  et al. Efficacy, but not antibody titer or affinity, of a heroin hapten conjugate vaccine correlates with increasing hapten densities on tetanus toxoid, but not on CRM197 carriers. Bioconjug Chem 26:1041-53 (2015). ELISA ; Mouse . Read more (PubMed: 25970207) »

See 1 Publication for this product

Product Wall

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We have not mapped the exact epitope that ab53827 binds too and so I am unable to let you know whether it does bind within amino acids 1-389 or not.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"