Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence

    Associated products

    Specifications

    Our Abpromise guarantee covers the use of ab191381 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Blocking - Blocking peptide for Anti-Dishevelled 3 antibody [EP1991Y] (ab76081)

    • Form
      Liquid
    • Additional notes

      This is an immunizing peptide for ab76081.

      - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
      - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
      - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
      - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
      - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at -20°C or -80°C.

    General Info

    • Alternative names
      • Dishevelled 3
      • Dishevelled 3 (homologous to Drosophila dsh)
      • Dishevelled 3, dsh homolog (Drosophila)
      • Dishevelled, dsh homolog 3 (Drosophila)
      • Dishevelled-3
      • DSH homolog 3
      • dvl3
      • DVL3_HUMAN
      • KIAA0208
      • OTTHUMP00000210777
      • OTTHUMP00000210778
      • Segment polarity protein dishevelled homolog DVL 3
      • Segment polarity protein dishevelled homolog DVL-3
      see all
    • Function
      May play a role in the signal transduction pathway mediated by multiple Wnt genes.
    • Sequence similarities
      Belongs to the DSH family.
      Contains 1 DEP domain.
      Contains 1 DIX domain.
      Contains 1 PDZ (DHR) domain.
    • Post-translational
      modifications
      Ubiquitinated. Deubiquitinated by CYLD, which acts on 'Lys-63'-linked ubiquitin chains.
    • Cellular localization
      Cytoplasm.
    • Information by UniProt

    References

    ab191381 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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