|
|
|
|
|
Product Name
|
Dispatched antibody
|
| |
See all Dispatched antibodies (2)...
|
|
Product type
|
Primary antibodies
|
|
Description
|
Goat polyclonal to Dispatched
|
|
|
Note on antibody grade |
Fast-Track antibodies
- Immunogen affinity purified
- high ELISA titre values
- released early (to accelerate your research)
- 950 Abpoints to the 1st researcher
who submits conclusive data (positive or negative):
Read the Fast-Track antibody Terms of Use
|
 |
|
|
Immunogen
|
Synthetic peptide: SELSGESLLIKTL, corresponding to C terminal amino acids 1512-1524 of Human Dispatched.
BLAST 'SELSGESLLIKTL' with  or 
|
|
Predicted to react
(species key)
|
Hu, Ms, Rat
(Due to sequence homology)
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions
Peptide ELISA: antibody detection limit dilution 1/32000.
Western Blot: Preliminary experiments gave no signal but low background in Human Lung and A549 extracts at up to 1µg/ml.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
|
|
Cellular localization
|
Membrane; multi-pass membrane protein.
|
|
Research areas
|
Neuroscience >> Neurology process >> Neural Signal Transduction
|
|
Relevance
|
The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling.
Dispatched is a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells.
|
|
|
Dispatched antibody (ab10142) |
|
Database links
|
The links below go to external sites and will open in a new browser window |
|
Raised in
|
Goat
|
|
Clonality
|
Polyclonal
|
|
Isotype
|
IgG
|
|
Purity
|
Immunogen affinity purified
|
|
Storage buffer
|
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris-saline. pH 7.3 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
|
|
Purification notes
|
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
|
|
Form
|
Liquid
|
|
Concentration
|
0.500 mg/ml
|
|
Storage instructions
|
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Dispatched antibody is on this datasheet. But please do contact us if you would like any reassurance! |
|
|
| |
|
Search PubMed (MEDLINE) for references to Dispatched
|
| |
Dispatched antibody - more information
|
Customer reviews (feedback) regarding Dispatched antibody |
Customer FAQs regarding Dispatched antibody |
Protocols for Dispatched antibody |
Price and availability of products related to Dispatched antibody |
| |
Dispatched antibody - related products:
|
|
|
| |
Dispatched antibody - other tools:
|
Contact Abcam with a Technical Enquiry about Dispatched antibody |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
