Overview

  • Product name
    Anti-DKFZP434B168 antibody
    See all DKFZP434B168 primary antibodies
  • Description
    Rabbit polyclonal to DKFZP434B168
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Horse, Chicken, Cow, Dog, Turkey, Pig, Chimpanzee, Ferret, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to a region within the C terminal amino acids 850-900 of human DKFZP434B168 (TrEMBL entry Q9NVH2; GeneID 25896).

  • Positive control
    • Human breast carcinoma, human testicular seminoma

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Affinity purified using an epitope to DKFZP434B168 immobilised on solid support.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab87276 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: 1/100 - 1/500. Epitope exposure is recommended.
    Epitope exposure with tris EDTA pH 9.0 buffer will enhance staining.
    Likely to work with frozen sections

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Plays a role in DNA damage response (DDR) signaling during the S phase.
    • Sequence similarities
      Belongs to the Integrator subunit 7 family.
    • Cellular localization
      Nucleus. Chromosome. Localizes to sites of DNA damage in a H2AX-independent manner.
    • Information by UniProt
    • Database links
    • Alternative names
      • INTS7 antibody
      • 5930412E23Rik antibody
      • C1orf73 antibody
      • Chromosome 1 open reading frame 73 antibody
      • chunp6916 antibody
      • DKFZp434B168 antibody
      • FLJ10736 antibody
      • FLJ12447 antibody
      • Int7 antibody
      • INT7_HUMAN antibody
      • Integrator complex subunit 7 antibody
      • Ints7 antibody
      • Ints7 integrator complex subunit 7 antibody
      • OTTHUMP00000035211 antibody
      • RGD1308014 antibody
      see all

    Images

    • ab87276, at a 1/250 dilution, staining DKFZP434B168 in formalin fixed, paraffin embedded human breast carcinoma tissue by Immunohistochemistry. Detection: DAB staining

    References

    ab87276 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab87276.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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