Overview

  • Product nameAnti-DLEC1 antibody
    See all DLEC1 primary antibodies
  • Description
    Rabbit polyclonal to DLEC1
  • Tested applicationsSuitable for: IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence, corresponding to internal sequence amino acids 186-298 of Human DLEC1.

  • Positive control
    • Human cerebral cortex tissue; U 2 OS cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab121589 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml. Fixation/Permeabilization: PFA/Triton X-100

Target

  • FunctionMay act as a tumor suppressor by inhibiting cell proliferation.
  • Tissue specificityExpressed in all tissues examined. Expression is highest in prostate and testis.
  • Involvement in diseaseDLEC1 silencing due to promoter methylation and aberrant transcription are implicated in the development of different cancers, including esophageal (ESCR), renal and lung cancers (LNCR).
    Lung cancer
    Esophageal cancer
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Deleted in lung and esophageal cancer 1 antibody
    • Deleted in lung and esophageal cancer 1 transcript varient 2 antibody
    • Deleted in lung and esophageal cancer protein 1 antibody
    • Deleted in lung cancer protein 1 antibody
    • DLC 1 antibody
    • Dlc-1 antibody
    • DLC1 antibody
    • Dlec1 antibody
    • DLEC1_HUMAN antibody
    • F56 antibody
    see all

Anti-DLEC1 antibody images

  • ab121589, at a 1/225 dilution, staining DLEC1 in neuronal cells of paraffin-embedded Human cerebral cortex by Immunohistochemistry.
  • ab121589, at 4 µg/ml, staining DLEC1 in PFA/Triton X-100 treated U 2 OS cells by immunofluorescence (green).

References for Anti-DLEC1 antibody (ab121589)

ab121589 has not yet been referenced specifically in any publications.

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