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Rabbit polyclonal to DLEC1
Synthetic peptide conjugated to KLH, corresponding to N terminal amino acids 262-292 of Human DLEC1 (NP_031361.2, NP_031363.2, Q9Y238).
NCI-H460 cell line lysates
Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
Preservative: 0.09% Sodium azide
Constituent: 99% PBS
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Immunogen affinity purified
This antibody is purified through a protein A column, followed by peptide affinity purification
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 195 kDa.
May act as a tumor suppressor by inhibiting cell proliferation.
Expressed in all tissues examined. Expression is highest in prostate and testis.
Involvement in disease
DLEC1 silencing due to promoter methylation and aberrant transcription are implicated in the development of different cancers, including esophageal (ESCR), renal and lung cancers (LNCR).
Lung cancer Esophageal cancer
Information by UniProt
Deleted in lung and esophageal cancer 1 antibody
Deleted in lung and esophageal cancer 1 transcript varient 2 antibody
Deleted in lung and esophageal cancer protein 1 antibody
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"