Overview

  • Product nameAnti-DLG5 antibody
    See all DLG5 primary antibodies
  • Description
    Mouse monoclonal to DLG5
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 1708-1810 of Human DLG5

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG1
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab56492 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration. PubMed: 21294127
WB Use a concentration of 1 - 5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

Target

  • FunctionMay play a role at the plasma membrane in the maintenance of the structure of epithelial cells and in the transmission of extracellular signals to the membrane and cytoskeleton.
  • Tissue specificityHighly expressed in the placenta and prostate. Expressed at a lower level in the thyroid, spinal cord, trachea, adrenal gland, skeletal muscle, pancreas, heart, brain, liver and kidney. A short splice product shows more limited expression, being absent from at least the brain.
  • Sequence similaritiesBelongs to the MAGUK family.
    Contains 1 CARD domain.
    Contains 1 guanylate kinase-like domain.
    Contains 4 PDZ (DHR) domains.
    Contains 1 SH3 domain.
  • Cellular localizationCell junction. Cell membrane. Localized at sites of cell-cell contact.
  • Information by UniProt
  • Database links
  • Alternative names
    • Discs large homolog 5 (Drosophila) antibody
    • Discs large homolog 5 antibody
    • Discs large protein LP DLG antibody
    • Discs large protein P dlg antibody
    • Discs large protein P-dlg antibody
    • Disks large homolog 5 antibody
    • DLG 5 antibody
    • DLG5 antibody
    • DLG5_HUMAN antibody
    • KIAA0583 antibody
    • Large type of P DLG antibody
    • LP DLG antibody
    • P DLG5 antibody
    • PDLG antibody
    • Placenta and prostate DLG antibody
    see all

Anti-DLG5 antibody images

  • Western blot against tagged recombinant protein immunogen using ab56492 DLG5 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

References for Anti-DLG5 antibody (ab56492)

This product has been referenced in:
  • Saben J  et al. A comprehensive analysis of the human placenta transcriptome. Placenta 35:125-31 (2014). Human . Read more (PubMed: 24333048) »
  • Ruiz C  et al. Amplification and overexpression of vinculin are associated with increased tumour cell proliferation and progression in advanced prostate cancer. J Pathol 223:543-52 (2011). IHC-P ; Human . Read more (PubMed: 21294127) »

See all 2 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab56492.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"