Overview

  • Product name
  • Description
    Rabbit polyclonal to DLGAP2
  • Specificity
    ab106520 will not cross-react with other SAPAP proteins.
  • Tested applications
    Suitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A 16 amino acid synthetic peptide from near the center of Human DLGAP2 (UniProt Q9P1A6).

  • Positive control
    • WB: Raji and L1210 cell lysates; ICC/IF: Human brain cells.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (stable for up to 12 months).
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106520 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 118 kDa.
IHC-P Use at an assay dependent concentration.

Target

  • Function
    May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.
  • Tissue specificity
    Expressed in brain and kidney.
  • Sequence similarities
    Belongs to the SAPAP family.
  • Cellular localization
    Cell membrane. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse. Postsynaptic density of neuronal cells.
  • Information by UniProt
  • Database links
  • Alternative names
    • DAP-2 antibody
    • DAP2 antibody
    • Discs large (Drosophila) homolog associated protein 2 antibody
    • Discs large homolog associated protein 2 antibody
    • Disks large-associated protein 2 antibody
    • Dlgap2 antibody
    • DLGP2_HUMAN antibody
    • PSD-95/SAP90-binding protein 2 antibody
    • SAP90/PSD-95-associated protein 2 antibody
    • SAPAP2 antibody
    see all

Images

  • Lane 1 : Anti-DLGAP2 antibody (ab106520) at 0.5 µg/ml
    Lane 2 : Anti-DLGAP2 antibody (ab106520) at 1 µg/ml

    Lane 1 : Raji (human Burkitt's lymphoma cell line) cell lysate
    Lane 2 : Raji (human Burkitt's lymphoma cell line) cell lysate


    Predicted band size : 118 kDa
  • Lane 1 : Anti-DLGAP2 antibody (ab106520) at 0.5 µg/ml
    Lane 2 : Anti-DLGAP2 antibody (ab106520) at 1 µg/ml

    Lane 1 : L1210 cell lysate
    Lane 2 : L1210 cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 118 kDa
  • Immunofluorescence of SAPAP2 in Human Brain cells using ab106520 at 20 ug/ml.

References

ab106520 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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