The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 51 kDa (predicted molecular weight: 41 kDa).
FunctionMay have a role in neuroendocrine differentiation.
Tissue specificityFound within the stromal cells in close contact to the vascular structure of placental villi, yolk sac, fetal liver, adrenal cortex and pancreas and in the beta cells of the islets of Langerhans in the adult pancreas. Found also in some forms of neuroendocrine lung tumor tissue.
Sequence similaritiesContains 6 EGF-like domains.
Post-translational modificationsN- and O-glycosylated.