Overview

  • Product nameAnti-DLL1 antibody [4F8]
    See all DLL1 primary antibodies
  • Description
    Mouse monoclonal [4F8] to DLL1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: QVWSSGVFEL KLQEFVNKKG LLGNRNCCRG GAGPPPCACR TFFRVCLKHY QASVSPEPPC TYGSAVTPVL GVDSFSLPDG GGADSAFSNP IR, corresponding to amino acids 18-110 of Human Delta like 1

Properties

Applications

Our Abpromise guarantee covers the use of ab57308 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionActs as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
    • Tissue specificityExpressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney.
    • Sequence similaritiesContains 1 DSL domain.
      Contains 8 EGF-like domains.
    • Post-translational
      modifications
      Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Delta (Drosophila) like 1 antibody
      • Delta antibody
      • Delta like 1 (Drosophila) antibody
      • Delta like 1 antibody
      • Delta like 1 protein antibody
      • Delta like protein 1 antibody
      • Delta like protein 1 precursor antibody
      • Delta, Drosophila, homolog of 1 antibody
      • Delta-like protein 1 antibody
      • Delta1 antibody
      • DL1 antibody
      • DLL 1 antibody
      • DLL1 antibody
      • DLL1_HUMAN antibody
      • Drosophila Delta homolog 1 antibody
      • H-Delta-1 antibody
      • OTTHUMP00000017690 antibody
      see all

    Anti-DLL1 antibody [4F8] images

    • Western blot against tagged recombinant protein immunogen using ab57308 Delta like 1 antibody at 1ug/ml. Predicted band size of immunogen is 36 kDa

    References for Anti-DLL1 antibody [4F8] (ab57308)

    ab57308 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab57308.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"