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Goat polyclonal to DLL4
Mouse, Rat, Human
Synthetic peptide corresponding to Human DLL4 aa 586-598 (internal sequence). NP_061947.1.
Human, mouse and rat lung lysates.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Preservative: 0.02% Sodium azide Constituents: 99% Tris buffered saline, 0.5% BSA
Concentration information loading...
Immunogen affinity purified
ab183532 was purified from goat serum by ammonium sulfate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Immunizing Peptide (Blocking)
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.1 - 1 µg/ml. Detects a band of approximately 80-85 kDa (predicted molecular weight: 74 kDa).Can be blocked with
DLL4 peptide (ab212174).
Plays a role in the Notch signaling pathway. Activates Notch-1 and Notch-4.
Expressed in vascular endothelium.
Contains 1 DSL domain.
Contains 8 EGF-like domains.
The Delta-Serrate-Lag2 (DSL) domain is required for binding to the Notch receptor.
Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.
Information by UniProt
Delta 4 antibody
delta 4 precursor antibody
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