Overview

  • Product name
    Anti-DMXL2 antibody
  • Description
    Rabbit polyclonal to DMXL2
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: TKTSALSAKK DQPDFISHRM DDVPSHSKAL SDGNGSSGIE WSNVTSSQYD WSQPIVKVDE EPLNLDWGED HDSALDEEED DAVGLVMKST DA, corresponding to internal sequence amino acids 1912-2003 of Human DMXL2.

  • Positive control
    • Human testis tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab122552 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    May serve as a scaffold protein for MADD and RAB3GA on synaptic vesicles.
  • Sequence similarities
    Contains 16 WD repeats.
  • Cellular localization
    Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • DmX-like protein 2 antibody
    • Dmxl2 antibody
    • DMXL2_HUMAN antibody
    • KIAA0856 antibody
    • Rabconnectin-3 antibody
    • RC3 antibody
    see all

Images

  • ab122552, at 1/50 dilution, staining DMXL2 in Paraffin-embedded Human testis tissue by Immunohistochemistry.

References

This product has been referenced in:
  • Faronato M  et al. DMXL2 drives epithelial to mesenchymal transition in hormonal therapy resistant breast cancer through Notch hyper-activation. Oncotarget 6:22467-79 (2015). IHC-P ; Human . Read more (PubMed: 26093085) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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