ab103970 is a DNA Damage Kinases Panel designed for the validation and characterization of the phosphorylation state of the DNA damage responsive kinases ATM and DNA-PKcs. ATM and DNA-PK are protein kinases that are active and become phosphorylated in response to DNA double strand breaks (DSBs). ATM is phosphorylated on S1981 and phosphorylates various proteins during the cellular response to DNA DSBs, while DNA-PK, a key component of the non-homologous end-joining pathway of DSB repair, is phosphorylated on S2056.
|ab18192 - Anti-DNA PKcs (phospho S2056) antibody - ChIP Grade||1 x 25µg|
|ab36810 - Anti-ATM (phospho S1981) antibody [10H11.E12]||1 x 25µg|
|ab70250 - Anti-DNA PKcs antibody||1 x 25µl|
|ab82512 - Anti-ATM antibody||1 x 25µg|