Overview

  • Product name
    Anti-DNA Ligase III antibody
    See all DNA Ligase III primary antibodies
  • Description
    Rabbit polyclonal to DNA Ligase III
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to a region between residue 1650 and 1700 of Human DNA Ligase III (NP_036247.1)

  • Positive control
    • Human Controls: Breast Carcinoma, Ovarian Carcinoma, Prostate Carcinoma, Small Cell Lung Cancer. Mouse Controls: Colon Carcinoma CT26, Teratoma.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab84749 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: 1/100 - 1/500. Epitope exposure with citrate buffer will enhance staining.
    Likely to work with frozen sections


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Interacts with DNA-repair protein XRCC1 and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents.
    • Tissue specificity
      Testis, thymus, prostate and heart.
    • Sequence similarities
      Belongs to the ATP-dependent DNA ligase family.
      Contains 1 BRCT domain.
      Contains 1 PARP-type zinc finger.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • D11Wsu78e antibody
      • DNA ligase antibody
      • DNA ligase 3 antibody
      • DNA ligase III antibody
      • DNLI3_HUMAN antibody
      • LIG 3 antibody
      • LIG2 antibody
      • LIG3 antibody
      • Ligase II, DNA, ATP dependent antibody
      • Ligase III DNA ATP dependent antibody
      • MGC78176 antibody
      • OTTMUSP00000000875 antibody
      • Polydeoxyribonucleotide synthase [ATP] 3 antibody
      • Polydeoxyribonucleotide synthase [ATP] antibody
      • Polydeoxyribonucleotide synthase antibody
      • RP23-316C11.6 antibody
      see all

    Images

    • ab84749 at 1/250 dilution binding FLASH on Human prostate nodular hypertrophy tissue sections by immunohistochemistry. Detection: DAB staining.
    • ab84749 at 1/250 dilution binding FLASH on Mouse teratoma tissue sections by immunohistochemistry. Detection: DAB staining.
    • ab84749 at 1/100 dilution binding FLASH on Human breast carcinoma tissue sections by immunohistochemistry. Detection: 1/100 red-fluorescent goat anti-rabbit IgG highly cross-adsorbed antibody Hilyte PlusTM 555.

    References

    ab84749 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab84749.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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