Anti-DNA Polymerase beta antibody [SPM177], prediluted (ab53923)

Overview

  • Product nameAnti-DNA Polymerase beta antibody [SPM177], prediluted
    See all DNA Polymerase beta primary antibodies
  • Description
    Mouse monoclonal [SPM177] to DNA Polymerase beta, prediluted
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    DNA polymerase beta protein.

  • Positive control
    • Hela cells and human testis.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab53923 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: Ready to use for 60 min at room temperature .

    Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionRepair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
    • Sequence similaritiesBelongs to the DNA polymerase type-X family.
    • DomainResidues 239-252 form a flexible loop which appears to affect the polymerase fidelity.
    • Post-translational
      modifications
      Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • DNA directed DNA polymerase beta antibody
      • DNA pol beta antibody
      • DNA polymerase beta antibody
      • DNA polymerase beta subunit antibody
      • DPOLB_HUMAN antibody
      • MGC125976 antibody
      • Pol B antibody
      • Pol beta antibody
      • POLB antibody
      • Polymerase (DNA directed) beta antibody
      see all

    Anti-DNA Polymerase beta antibody [SPM177], prediluted images

    • ab53923 (prediluted) staining DNA Polymerase Beta in formalin fixed, paraffin embedded human testis tissue by Immunohistochemistry.

    References for Anti-DNA Polymerase beta antibody [SPM177], prediluted (ab53923)

    ab53923 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"