Anti-DNA Polymerase lambda antibody (ab103234)

Overview

  • Product nameAnti-DNA Polymerase lambda antibody
    See all DNA Polymerase lambda primary antibodies
  • Description
    Rabbit polyclonal to DNA Polymerase lambda
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 546-575 of Human DNA Polymerase lambda

  • Positive control
    • HepG2 cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityAmmonium Sulphate Precipitation
  • Purification notesab103234 is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab103234 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Predicted molecular weight: 63 kDa.

Target

  • FunctionRepair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
  • Tissue specificityExpressed in a number of tissues. Abundant in testis.
  • Sequence similaritiesBelongs to the DNA polymerase type-X family.
    Contains 1 BRCT domain.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • BETA N antibody
    • BETAN antibody
    • DNA directed DNA polymerase lambda antibody
    • DNA polymerase beta 2 antibody
    • DNA polymerase beta-2 antibody
    • DNA polymerase kappa antibody
    • DNA polymerase kappa DNA polymerase beta N antibody
    • DNA polymerase lambda antibody
    • DNA polymerase lamda2 antibody
    • DPOLL_HUMAN antibody
    • EC 2.7.7.7,EC 4.2.99. antibody
    • FLJ46002 antibody
    • OTTHUMP00000020321 antibody
    • OTTHUMP00000020323 antibody
    • OTTHUMP00000059179 antibody
    • Pol beta2 antibody
    • POL KAPPA antibody
    • Pol Lambda antibody
    • POLKAPPA antibody
    • POLL antibody
    • Polymerase DNA directed lambda antibody
    see all

Anti-DNA Polymerase lambda antibody images

  • Anti-DNA Polymerase lambda antibody (ab103234) at 1/50 dilution + HepG2 cell lysate at 35 µg

    Predicted band size : 63 kDa

References for Anti-DNA Polymerase lambda antibody (ab103234)

ab103234 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"