Anti-DNA Polymerase lambda antibody (ab84750)


  • Product nameAnti-DNA Polymerase lambda antibody
    See all DNA Polymerase lambda primary antibodies
  • Description
    Rabbit polyclonal to DNA Polymerase lambda
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Rabbit, Guinea pig, Cow, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region between residues 525 and 575 of human DNA Polymerase lambda (NP_037406.1)

  • Positive control
    • Human controls: Anaplastic Thyroid Carcinoma, Breast Carcinoma, Linitis Plastica Stomach Cancer, Ovarian Carcinoma, Pancreatic Islet Cell Tumor, Prostate Carcinoma, Stomach Adenocarcinoma, Testicular Seminoma tissues. Mouse controls: Teratoma tissue.
  • General notesAntibody concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG. Centrifuge microtube to remove product from lid.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab84750 was affinity purified using an epitope specific to DNA Polymerase lambda immobilized on solid support.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab84750 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesIHC-P: 1/100 - 1/500.
    Epitope exposure with citrate buffer will enhance staining.

    Likely to work with Frozen Sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionRepair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
    • Tissue specificityExpressed in a number of tissues. Abundant in testis.
    • Sequence similaritiesBelongs to the DNA polymerase type-X family.
      Contains 1 BRCT domain.
    • Post-translational
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • BETA N antibody
      • BETAN antibody
      • DNA directed DNA polymerase lambda antibody
      • DNA polymerase beta 2 antibody
      • DNA polymerase beta-2 antibody
      • DNA polymerase kappa antibody
      • DNA polymerase kappa DNA polymerase beta N antibody
      • DNA polymerase lambda antibody
      • DNA polymerase lamda2 antibody
      • DPOLL_HUMAN antibody
      • EC,EC 4.2.99. antibody
      • FLJ46002 antibody
      • OTTHUMP00000020321 antibody
      • OTTHUMP00000020323 antibody
      • OTTHUMP00000059179 antibody
      • Pol beta2 antibody
      • POL KAPPA antibody
      • Pol Lambda antibody
      • POLKAPPA antibody
      • POLL antibody
      • Polymerase DNA directed lambda antibody
      see all

    Anti-DNA Polymerase lambda antibody images

    • ab84750 at 1/250 dilution staining DNA Polymerase lambda in human prostate nodular hypertrophy by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.
    • ab84750 at 1/250 dilution staining DNA Polymerase lambda in mouse teratoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.

    References for Anti-DNA Polymerase lambda antibody (ab84750)

    ab84750 has not yet been referenced specifically in any publications.

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