The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration.
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
FunctionGap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.
Tissue specificityExpressed in a number of tissues. Abundant in thymus.
Sequence similaritiesBelongs to the DNA polymerase type-X family. Contains 1 BRCT domain.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DNA polymerase mu antibody (ab118890)
ab118890, at 5 µg/ml, staining DNA polymerase mu in Formalin-fixed, Paraffin-embedded Human Kidney tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
References for Anti-DNA polymerase mu antibody (ab118890)
has not yet been referenced specifically in any publications.
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