Overview

  • Product name
    Anti-DNA polymerase mu antibody
    See all DNA polymerase mu primary antibodies
  • Description
    Rabbit polyclonal to DNA polymerase mu
  • Tested applications
    Suitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    RRARVGSPSGDAA

    , corresponding to amino acids 6-18 of Human DNA polymerase mu.

  • Positive control
    • Human Kidney tissue.
  • General notes
    Store at 4°C or -20°C. Avoid repeated freezing and thawing.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Please see notes section.
  • Storage buffer
    pH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 0.27% Potassium phosphate, 0.88% Sodium chloride
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab118890 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.
  • Tissue specificity
    Expressed in a number of tissues. Abundant in thymus.
  • Sequence similarities
    Belongs to the DNA polymerase type-X family.
    Contains 1 BRCT domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • DNA-directed DNA polymerase mu antibody
    • DNA-directed DNA/RNA polymerase mu antibody
    • DPOLM_HUMAN antibody
    • FLJ35482 antibody
    • Pol iota antibody
    • Pol Mu antibody
    • Polm antibody
    • POLM protein antibody
    • Polymerase (DNA directed) mu antibody
    • Polymerase DNA directed mu antibody
    • Tdt N antibody
    • Tdt-N antibody
    • TdtN antibody
    • Terminal transferase antibody
    see all

Images

  • ab118890, at 5 µg/ml, staining DNA polymerase mu in Formalin-fixed, Paraffin-embedded Human Kidney tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References

ab118890 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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