Anti-DNA Polymerase theta antibody (ab111218)

Overview

  • Product nameAnti-DNA Polymerase theta antibody
    See all DNA Polymerase theta primary antibodies
  • Description
    Rabbit polyclonal to DNA Polymerase theta
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide: H FSSLDIAV CT IERANGL INR LIEENK MDLL GMVVV DELHM LGDS HRGYLL, corresponding to amino acids 180-230 of Human DNA Polymerase theta

  • Positive control
    • Human breast carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab111218 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionHas a DNA polymerase activity on nicked double-stranded DNA and on a singly primed DNA template. The enzyme activity is resistant to aphidicolin, and inhibited by dideoxynucleotides. Exhibites a single-stranded DNA-dependent ATPase activity. Could be involved in the repair of interstrand cross-links.
  • Tissue specificityHighly expressed in testis.
  • Sequence similaritiesBelongs to the DNA polymerase type-A family.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp781A0112 antibody
    • DNA polymerase eta antibody
    • DNA polymerase theta antibody
    • DPOLQ_HUMAN antibody
    • POLH antibody
    • POLQ antibody
    • Polymerase (DNA directed) theta antibody
    • PRO0327 antibody
    see all

Anti-DNA Polymerase theta antibody images

  • ab111218 at 1/50 dilution staining DNA Polymerase theta in paraffin-embedded Human Breast carcinoma tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

References for Anti-DNA Polymerase theta antibody (ab111218)

ab111218 has not yet been referenced specifically in any publications.

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