Overview

  • Product name
  • Description
    Mouse polyclonal to DNAJC15
  • Host species
    Mouse
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-150 of Human DNAJC15 (NP_037370).

  • Positive control
    • Lysate of 293T cells transfected with DNAJC15.

Properties

Applications

Our Abpromise guarantee covers the use of ab167199 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 16 kDa.

Target

  • Function
    Negative regulator of the mitochondrial respiratory chain. Prevents mitochondrial hyperpolarization state and restricts mitochondrial generation of ATP (By similarity). Acts as an import component of the TIM23 translocase complex. Stimulates the ATPase activity of HSPA9.
  • Tissue specificity
    Expressed at highest levels in heart, followed by liver and kidney.
  • Involvement in disease
    Absent or down-regulated in many advanced cases of ovarian adenocarcinoma, due to hypermethylation and allelic loss. Loss of expression correlates with increased resistance to antineoplastic drugs, such as cisplatin.
  • Sequence similarities
    Contains 1 J domain.
  • Cellular localization
    Mitochondrion inner membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cell growth inhibiting gene 22 protein antibody
    • Cell growth-inhibiting gene 22 protein antibody
    • DJC15_HUMAN antibody
    • DnaJ (Hsp40) homolog subfamily C member 15 antibody
    • DNAJ domain containing antibody
    • DnaJ homolog subfamily C member 15 antibody
    • DNAJC15 antibody
    • DNAJD1 antibody
    • GIG22 antibody
    • HSD18 antibody
    • MCJ antibody
    • Methylation controlled J protein antibody
    • Methylation-controlled J protein antibody
    see all

Images

  • All lanes : Anti-DNAJC15 antibody (ab167199) at 1 µg/ml

    Lane 1 : Lysate of 293T cells transfected with DNAJC15
    Lane 2 : Lysate of 293T cells (non-transfected)

    Lysates/proteins at 15 µl per lane.

    Secondary
    All lanes : Goat anti-mouse HRP conjugated antibody at 1/2500 dilution

    Predicted band size: 16 kDa

References

ab167199 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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