Overview

  • Product name
  • Description
    Rabbit polyclonal to DNase gamma
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 115-305 of Human DNase gamma (UniProt; Q13609).

  • Positive control
    • A549, HeLa, HepG2 and HCT116 whole cell lysates; HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab152118 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 36 kDa.
ICC/IF 1/100 - 1/1000.

Target

  • Function
    Has DNA hydrolytic activity. Does not bind to actin. Cleaves chromatin DNA to nucleosomal units.
  • Tissue specificity
    Liver and spleen.
  • Sequence similarities
    Belongs to the DNase I family.
  • Cellular localization
    Nucleus. May first pass through the ER membrane before being imported in the nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Deoxyribonuclease gamma antibody
    • Deoxyribonuclease I like 3 antibody
    • Deoxyribonuclease I like III antibody
    • Deoxyribonuclease I-like 3 antibody
    • DHP 2 antibody
    • DHP2 antibody
    • DNAS1L3 antibody
    • DNase gamma antibody
    • DNase I homolog protein 2 antibody
    • DNase I homolog protein DHP2 antibody
    • DNase I like 3 antibody
    • DNase I-like 3 antibody
    • DNASE1L3 antibody
    • DNSL3_HUMAN antibody
    • Liver and spleen DNase antibody
    • LS DNase antibody
    • LS-DNase antibody
    • LSD antibody
    • SLEB 16 antibody
    • SLEB16 antibody
    see all

Images

  • Anti-DNase gamma antibody (ab152118) at 1/1000 dilution + HCT116 whole cell lysate at 30 µg

    Predicted band size : 36 kDa
  • Immunofluorescent analysis of paraformaldehyde-fixed HeLa cells, labeling DNase gamma with ab152118 at 1/200 dilution. Lower image shows cells co-stained with Hoechst 33342.

References

ab152118 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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