Overview

  • Product name
    Anti-DNASE2B antibody
  • Description
    Rabbit polyclonal to DNASE2B
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 130-275 of Human DNASE2B (AAI26137).

  • Positive control
    • HCT116 whole cell lysate; A549, HeLa and HepG2 cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab104216 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 42 kDa.

Target

  • Relevance
    DNASE2B shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this protein is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.
  • Cellular localization
    Lysosome
  • Database links
  • Alternative names
    • Deoxyribonuclease 2 beta antibody
    • Deoxyribonuclease 2 beta precursor antibody
    • Deoxyribonuclease II beta antibody
    • DLAD antibody
    • DNase 2 like acid DNase antibody
    • DNASE 2B antibody
    • DNase II beta antibody
    • DNase II like acid DNase antibody
    • DNASE2 antibody
    • DNase2 like acid DNase antibody
    • DnaseIIb antibody
    • EC 3.1.22.1 antibody
    • Endonuclease DLAD antibody
    • Lysosomal DNase II antibody
    • UOX antibody
    see all

Images

  • Anti-DNASE2B antibody (ab104216) at 1/500 dilution + HCT116 whole cell lysate at 30 µg

    Predicted band size : 42 kDa

References

ab104216 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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