Overview

  • Product name
  • Description
    Rabbit polyclonal to DNER
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human DNER. The exact sequence is proprietary.
    Database link: Q8NFT8

  • Positive control
    • A549, RAW 264.7 and PC12 whole cell lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.2
    Preservative: 0.05% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab191913 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab191913 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Detects a band of approximately 70 kDa (predicted molecular weight: 78 kDa).

Target

  • Function
    Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.
  • Tissue specificity
    Expressed in brain, spinal cord and adrenal gland.
  • Sequence similarities
    Contains 10 EGF-like domains.
    Contains 1 follistatin-like domain.
  • Cellular localization
    Cell membrane. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity).
  • Information by UniProt
  • Database links
  • Alternative names
    • bet antibody
    • Brain EGF repeat-containing transmembrane protein antibody
    • Bret antibody
    • Delta and Notch-like epidermal growth factor-related receptor antibody
    • Delta notch like EGF repeat containing transmembrane antibody
    • Delta/notch like EGF repeat containing antibody
    • Delta/notch-like EGF-related receptor antibody
    • Dner antibody
    • DNER_HUMAN antibody
    • PRO299 antibody
    • Transmembrane protein Bet antibody
    • UNQ26 antibody
    see all

Images

  • All lanes : Anti-DNER antibody (ab191913)

    Lane 1 : A549 whole cell lysate
    Lane 2 : RAW 264.7 whole cell lysate
    Lane 3 : PC12 whole cell lysate


    Predicted band size : 78 kDa

References

ab191913 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab191913.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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