Overview

  • Product nameAnti-DNER antibody
    See all DNER primary antibodies
  • Description
    Mouse monoclonal to DNER
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 368-477 of Human DNER

  • Positive control
    • PC-12 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab57949 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Detects a band of approximately 90-100 kDa (predicted molecular weight: 78.4 kDa). Larger band size is due to glycosylation.

Target

  • FunctionActivator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.
  • Tissue specificityExpressed in brain, spinal cord and adrenal gland.
  • Sequence similaritiesContains 10 EGF-like domains.
    Contains 1 follistatin-like domain.
  • Cellular localizationCell membrane. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity).
  • Information by UniProt
  • Database links
  • Alternative names
    • bet antibody
    • Brain EGF repeat-containing transmembrane protein antibody
    • Bret antibody
    • Delta and Notch-like epidermal growth factor-related receptor antibody
    • Delta notch like EGF repeat containing transmembrane antibody
    • Delta/notch like EGF repeat containing antibody
    • Delta/notch-like EGF-related receptor antibody
    • Dner antibody
    • DNER_HUMAN antibody
    • PRO299 antibody
    • Transmembrane protein Bet antibody
    • UNQ26 antibody
    see all

Anti-DNER antibody images



  • Predicted band size : 78.4 kDa

    Western Blot analysis of DNER antibody (ab57949).

References for Anti-DNER antibody (ab57949)

ab57949 has not yet been referenced specifically in any publications.

Product Wall

Thank you for the inquiry. The calculated predicted molecular weight of DNER is indeed 78.4KDa but the protein is glycosylated, hence when testing on PC12 cell lysate a band at around 100kDa was detected. This band size has been reported in the lit...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"