Overview

  • Product name
    DNMT3B Inhibitor Screening Assay Kit
    See all DNMT3B kits
  • Assay type
    Enzyme activity
  • Assay time
    3h 00m
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Mammal
  • Product overview

    DNMT3B (DNA (cytosine-5)-methyltransferase 3B) belongs to the DNMT family, it is required for genome de novo methylation and it is essential for establishment of DNA methylation patterns during development. The selective inhibition of DNMT3B may lead to demethylation and expression of silenced tumor suppressor genes. Thus, the selective DNMT3B inhibitors could be a new addition to cancer therapeutic agents.

    Abcam's DNMT3B Inhibitor Screening Assay Kit (ab113466) allows the user to selectively screen DNMT3B activity/inhibitors in an ELISA-like format. The kit is ready-to-use and provides all the essential components needed to carry out a successful DNMT3B activity/inhibitor screening experiment without the need for radioactivity or any special equipment.

    Not sure if this is the right product for you? Check out our DNMT Product Guide for help.

  • Tested applications
    Suitable for: Functional Studiesmore details

Properties

Applications

Our Abpromise guarantee covers the use of ab113466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Functional Studies Use at an assay dependent concentration.

Images

  • Optical densities representing inhibition of 500ng DNMT3b (ab170410) by various concentrations of OM173-alpha A (ab144849)

  • Inhibition of 500ng DNMT3B (ab170410) by various concentrations of OM173-alphaA (ab144849)

Protocols

References

ab113466 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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