Overview

  • Product name
  • Description
    Rabbit polyclonal to DOCK11
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human DOCK11 aa 583-628.
    Database link: Q5JSL3

  • Positive control
    • HeLa, Raw264.7 and PC12 whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab192390 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 238 kDa.

Target

  • Function
    Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.
  • Sequence similarities
    Belongs to the DOCK family.
    Contains 1 DHR-1 (CZH-1) domain.
    Contains 1 DHR-2 (CZH-2) domain.
    Contains 1 PH domain.
  • Domain
    The DHR-2 domain is necessary for the GEF activity.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Information by UniProt
  • Database links
  • Alternative names
    • ACG antibody
    • Activated Cdc42-associated guanine nucleotide exchange factor antibody
    • Dedicator of cytokinesis protein 11 antibody
    • DOC11_HUMAN antibody
    • Dock11 antibody
    • ZIZ2 antibody
    • Zizimin-2 antibody
    see all

Images

  • All lanes : Anti-DOCK11 antibody (ab192390)

    Lane 1 : HeLa whole cell lysate
    Lane 2 : Raw264.7 whole cell lysate
    Lane 3 : PC12 whole cell lysate

    Predicted band size: 238 kDa

References

ab192390 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab192390.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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