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Rabbit polyclonal to DOCK11
Mouse, Rat, Human
Synthetic peptide corresponding to Human DOCK11 aa 583-628.
Database link: Q5JSL3
- HeLa, Raw264.7 and PC12 whole cell lysates.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Preservative: 0.1% Sodium azide
Constituents: 49% PBS, 50% Glycerol
Concentration information loading...
Immunogen affinity purified
ab192390 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use at an assay dependent concentration. Predicted molecular weight: 238 kDa.
Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.
Belongs to the DOCK family.
Contains 1 DHR-1 (CZH-1) domain.
Contains 1 DHR-2 (CZH-2) domain.
Contains 1 PH domain.
The DHR-2 domain is necessary for the GEF activity.
Phosphorylated upon DNA damage, probably by ATM or ATR.
Information by UniProt
- ACG antibody
- Activated Cdc42-associated guanine nucleotide exchange factor antibody
- Dedicator of cytokinesis protein 11 antibody
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"