Overview

  • Product nameAnti-DOCK7 antibody [3540C1a]
    See all DOCK7 primary antibodies
  • Description
    Mouse monoclonal [3540C1a] to DOCK7
  • Tested applicationsSuitable for: WB, Dot blotmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment with a tag, corresponding to internal sequence amino acids 1003-1112 of Human DOCK7

  • Positive control
    • Immunising recombinant Human DOCK7 protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab84866 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 243 kDa.
Dot blot Use at an assay dependent dilution.

Target

  • RelevanceDOCK7 functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. It does not have a GEF activity for CDC42. It is required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization.
  • Cellular localizationCell projection, axon. Note=Enriched in the developing axons of hippocampal neurons.
  • Database links
  • Alternative names
    • 3110056M06Rik antibody
    • dedicator of cytokinesis 7 antibody
    • Dedicator of cytokinesis protein 7 antibody
    • Gm430 antibody
    • KIAA1771 antibody
    • MGC189434 antibody
    • mKIAA1771 antibody
    • RP23 329P19.2 antibody
    • ZIR2 antibody
    see all

Anti-DOCK7 antibody [3540C1a] images

References for Anti-DOCK7 antibody [3540C1a] (ab84866)

ab84866 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"