Overview

  • Product nameAnti-DOCK7 antibody
    See all DOCK7 primary antibodies
  • Description
    Mouse polyclonal to DOCK7
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Protein fragment corresponding to amino acids 1-624 of full length human DOCK7 protein (AAH16392.1).

  • Positive control
    • DOCK7 transfected 293T lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab71858 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 72 kDa (predicted molecular weight: 72 kDa).

Target

  • RelevanceDOCK7 functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. It does not have a GEF activity for CDC42. It is required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization.
  • Cellular localizationCell projection, axon. Note=Enriched in the developing axons of hippocampal neurons.
  • Database links
  • Alternative names
    • 3110056M06Rik antibody
    • dedicator of cytokinesis 7 antibody
    • Dedicator of cytokinesis protein 7 antibody
    • Gm430 antibody
    • KIAA1771 antibody
    • MGC189434 antibody
    • mKIAA1771 antibody
    • RP23 329P19.2 antibody
    • ZIR2 antibody
    see all

Anti-DOCK7 antibody images

  • All lanes : Anti-DOCK7 antibody (ab71858) at 1/500 dilution

    Lane 1 : DOCK7 transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 72 kDa
    Observed band size : 72 kDa

References for Anti-DOCK7 antibody (ab71858)

ab71858 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"