Anti-Dopamine Receptor D5 antibody, prediluted (ab32621)

Overview

  • Product nameAnti-Dopamine Receptor D5 antibody, prediluted
    See all Dopamine Receptor D5 primary antibodies
  • Description
    Rabbit polyclonal to Dopamine Receptor D5, prediluted
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chicken
  • Immunogen

    Synthetic peptide:

    CEGEISLDKI TPFTPNGFH

    , corresponding to C terminal amino acids 459-477 of Human Dopamine Receptor D5.

  • Positive control
    • Human brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab32621 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: Use Neat for 30 min at room temperature. Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionDopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
    • Tissue specificityNeuron-specific, localized primarily within limbic regions of the brain.
    • Involvement in diseaseDefects in DRD5 are a cause of benign essential blepharospasm (BEB) [MIM:606798]. BEB is a primary focal dystonia affecting the orbicularis oculi muscles. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. BEB usually begins in middle age. Initial symptoms include eye irritation and frequent blinking, progressing to involuntary spasms of eyelid closure. Patients have normal eyes. The visual disturbance is due solely to the forced closure of the eyelids. In severe cases, this can lead to functional blindness.
    • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
    • Cellular localizationCell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • D(1B) dopamine receptor antibody
      • D(5) dopamine receptor antibody
      • D1 beta dopamine receptor antibody
      • D1B dopamine receptor antibody
      • D1beta dopamine receptor antibody
      • D5 dopamine receptor antibody
      • DBDR antibody
      • Dopamine D5 receptor antibody
      • Dopamine receptor D1B antibody
      • dopamine receptor D5 antibody
      • DRD 1B antibody
      • DRD 5 antibody
      • DRD1B antibody
      • DRD1L2 antibody
      • DRD5 antibody
      • DRD5_HUMAN antibody
      • MGC10601 antibody
      see all

    Anti-Dopamine Receptor D5 antibody, prediluted images

    • Ab32621, prediluted, staining Dopamine Receptor D5 in formalin fixed paraffin embedded human brain tissue sections by Immunohistochemistry.

    References for Anti-Dopamine Receptor D5 antibody, prediluted (ab32621)

    ab32621 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"