Anti-Dopamine Transporter antibody (ab78534)

Overview

  • Product nameAnti-Dopamine Transporter antibody
    See all Dopamine Transporter primary antibodies
  • Description
    Rabbit polyclonal to Dopamine Transporter
  • SpecificityDopamine Transporter, Extracellular loop 2 (EL2).
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human, Monkey
    Does not react with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human Dopamine Transporter (extracellular). Extracellular Loop 2.

  • Positive control
    • WB: SDS solubilized human striatal samples IHC-P: formaldehyde fixed human and monkey brain sections

Properties

Applications

Our Abpromise guarantee covers the use of ab78534 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 69 kDa.
IHC-P 1/500 - 1/1000.

Target

  • FunctionAmine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.
  • Involvement in diseaseDefects in SLC6A3 are the cause of dystonia-parkinsonism infantile (DYTPRI) [MIM:613135]. It is a neurodegenerative disorder characterized by infantile onset of parkinsonism and dystonia. Other neurologic features include global developmental delay, bradikinesia and pyramidal tract signs.
  • Sequence similaritiesBelongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • DA transporter antibody
    • DAT 1 antibody
    • DAT antibody
    • DAT1 antibody
    • Dopamine transporter 1 antibody
    • Dopamine transporter antibody
    • PKDYS antibody
    • SC6A3_HUMAN antibody
    • SLC6A3 antibody
    • Sodium dependent dopamine transporter antibody
    • Sodium-dependent dopamine transporter antibody
    • Solute carrier family 6 (neurotransmitter transporter dopamine), member 3 antibody
    • Solute carrier family 6 (neurotransmitter transporter), member 3 antibody
    • Solute carrier family 6 member 3 antibody
    • Variable number tandem repeat (VNTR) antibody
    see all

References for Anti-Dopamine Transporter antibody (ab78534)

ab78534 has not yet been referenced specifically in any publications.

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