Anti-DP1 antibody [SPM178], prediluted (ab53924)

Overview

  • Product nameAnti-DP1 antibody [SPM178], prediluted
    See all DP1 primary antibodies
  • Description
    Mouse monoclonal [SPM178] to DP1, prediluted
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant DP1 protein.

  • EpitopeAmino acids 83-204.
  • Positive control
    • MAD109 or Raji cells. Human tonsil.

Properties

Applications

Our Abpromise guarantee covers the use of ab53924 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: Ready to use for 30 min at room temperature.
    Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCan stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.
    • Tissue specificityHighest levels in muscle. Also expressed in brain, placenta, liver and kidney. Lower levels in lung and pancreas. Not detected in heart.
    • Sequence similaritiesBelongs to the E2F/DP family.
    • Post-translational
      modifications
      Phosphorylation by E2F-1-bound cyclin A-CDK2, in the S phase, inhibits E2F-mediated DNA binding and transactivation.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • DP 1 antibody
      • DP1 antibody
      • DRTF1 antibody
      • DRTF1-polypeptide 1 antibody
      • E2F dimerization partner 1 antibody
      • E2F related transcription factor antibody
      • TFDP1 antibody
      • TFDP1_HUMAN antibody
      • Transcription factor Dp-1 antibody
      • Transcription factor sequence-specific, DRTF1 antibody
      see all

    Anti-DP1 antibody [SPM178], prediluted images

    • ab53924 (prediluted) staining DP1 in formalin fixed, paraffin embedded human tonsil tissue by Immunohistochemistry.

    References for Anti-DP1 antibody [SPM178], prediluted (ab53924)

    ab53924 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"