Overview

  • Product name
  • Description
    Rabbit polyclonal to DPAGT1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, from a region within N terminal amino acids 27-57 of Human DPAGT1 (NP_001373.2).

  • Positive control
    • ZR-75-1 cell lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab116667 was purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG

Applications

Our Abpromise guarantee covers the use of ab116667 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 46 kDa.

Target

  • Function
    Catalyzes the initial step in the synthesis of dolichol-P-P-oligosaccharides.
  • Pathway
    Protein modification; protein glycosylation.
  • Involvement in disease
    Defects in DPAGT1 are the cause of congenital disorder of glycosylation type 1J (CDG1J) [MIM:608093]. CDGs are a family of severe inherited diseases caused by a defect in protein N-glycosylation. They are characterized by under-glycosylated serum proteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions.
  • Sequence similarities
    Belongs to the glycosyltransferase 4 family.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ALG7 antibody
    • AU021132 antibody
    • CDG Ij antibody
    • CDG1J antibody
    • CMS13 antibody
    • CMSTA2 antibody
    • D11S366 antibody
    • DGPT antibody
    • Dolichyl phosphate (UDP N acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc 1 P transferase) antibody
    • Dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 antibody
    • DPAGT1 antibody
    • DPAGT2 antibody
    • G1PT antibody
    • GlcNAc 1 P transferase 1 antibody
    • GlcNAc-1-P transferase antibody
    • Gnpta antibody
    • GPT antibody
    • GPT_HUMAN antibody
    • H2afx antibody
    • N-acetylglucosamine-1-phosphate transferase antibody
    • UAGT antibody
    • UDP GlcNAc:dolichyl phosphate N acetylglucosaminephosphotransferase antibody
    • UDP N acetylglucosamine dolichyl phosphate N acetylglucosaminephosphotransferase 1 antibody
    • UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase antibody
    • UGAT antibody
    see all

Images

  • Anti-DPAGT1 antibody (ab116667) at 1/100 dilution + ZR-75-1 cell lysate at 35 µg

    Predicted band size : 46 kDa

References

ab116667 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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