Overview

  • Product name
  • Description
    Rabbit polyclonal to DPEP1
  • Tested applications
    Suitable for: ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence corresponding to amino acids 136-247 of Human DPEP1.

  • Positive control
    • U-251 MG, Human Plasma and Human Tonsil lysates; Human kidney tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab121380 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity.
  • Sequence similarities
    Belongs to the peptidase M19 family.
  • Cellular localization
    Apical cell membrane. Cell projection > microvillus membrane. Brush border membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Dehydropeptidase-I antibody
    • Dipeptidase 1 (renal) antibody
    • Dipeptidase 1 antibody
    • DPEP1 antibody
    • DPEP1_HUMAN antibody
    • hRDP antibody
    • MBD1 antibody
    • MDP antibody
    • Microsomal dipeptidase antibody
    • RDP antibody
    • Renal dipeptidase antibody
    see all

Images

  • Immunocytochemistry/immunofluorescence analysis of HepG2 cells labelling DPEP1 with ab121380 shows positive staining in the nucleus and cell junctions.
  • ab121380 staining DPEP1 in Paraffin-emebedded Human kidney tissue by Immunohistochemistry.

References

ab121380 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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