This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

Overview

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab87617 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

  • Application notes
    WB: This antibody did not give bands in initial tests on lysate/cell line. We would welcome your feedback if you have tested this antibody in more suitable positive controls.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      DPM2 regulates the biosynthesis of dolichol phosphate-mannose. Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by DPM2 is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1.
    • Cellular localization
      Endoplasmic reticulum membrane; Multi-pass membrane protein.
    • Database links
    • Alternative names
      • Dolichol phosphate (beta D) mannosyltransferase 2 antibody
      • Dolichol phosphate mannose biosynthesis regulatory protein antibody
      • Dolichol phosphate mannose synthase 2 antibody
      • Dolichyl phosphate mannosyltransferase 2 antibody
      • Dolichyl phosphate mannosyltransferase polypeptide 2, regulatory subunit antibody
      • R75484 antibody
      • RP23 255P20.5 antibody
      see all

    References

    ab87617 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab87617.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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