Overview

  • Product name
  • Description
    Goat polyclonal to DPP10
  • Tested applications
    Suitable for: WB, IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow, Dog, Pig
  • Immunogen

    Synthetic peptide:

    C-DEGHNVSEKSKYHL

    , corresponding to internal sequence amino acids 756-769 of Human DPP10.

  • Positive control
    • Human brain cerebellum and cortex tissue; Human bone marrow lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab111985 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 91 kDa.
IHC-P Use a concentration of 3.75 µg/ml.
ELISA 1/32000.

Target

  • Function
    Has no dipeptidyl aminopeptidase activity. May modulate cell surface expression and activity of the potassium channels KCND1 and KCND2.
  • Tissue specificity
    Found in serum, T-cells and brain (at protein level). Expressed in brain, pancreas, spinal cord and adrenal glands.
  • Involvement in disease
    Genetic variations in DPP10 are associated with susceptibility to asthma (ASTHMA) [MIM:600807]. The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi.
  • Sequence similarities
    Belongs to the peptidase S9B family. DPPIV subfamily.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Dipeptidyl peptidase 10 antibody
    • Dipeptidyl peptidase 10 non functional antibody
    • Dipeptidyl peptidase IV related protein 3 antibody
    • Dipeptidyl peptidase IV-related protein 3 antibody
    • Dipeptidyl peptidase like protein 2 antibody
    • Dipeptidyl peptidase X antibody
    • Dipeptidyl peptidase-like protein 2 antibody
    • Dipeptidylpeptidase 10 antibody
    • DPL 2 antibody
    • DPL2 antibody
    • DPP 10 antibody
    • DPP X antibody
    • Dpp10 antibody
    • DPP10_HUMAN antibody
    • DPPY antibody
    • DPRP 3 antibody
    • DPRP-3 antibody
    • DPRP3 antibody
    • Inactive dipeptidyl peptidase 10 antibody
    • KIAA1492 antibody
    see all

Anti-DPP10 antibody images

  • ab111985, at 3.75 µg/ml, staining DPP10 in formalin-fixed, paraffin-embedded Human brain cerebellum tissue by Immunohistochemistry.
  • ab111985, at 3.75 µg/ml, staining DPP10 in formalin-fixed, paraffin-embedded Human brain cortex tissue by Immunohistochemistry.
  • Anti-DPP10 antibody (ab111985) at 0.1 µg/ml + Human bone marrow lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 91 kDa

References for Anti-DPP10 antibody (ab111985)

ab111985 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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