DPP10 antibody - Catalytic domain (ab42084)

Product Name 

DPP10 antibody - Catalytic domain

Product type 

Primary antibodies

Description 

Rabbit polyclonal to DPP10 - Catalytic domain

Immunogen 

Synthetic peptide corresponding to the catalytic domain of human DPP10.

(Peptide available as ab44606.)

Reacts with 
(species key)

Hu, Ms, Rat

Specificity 

This antibody recognises all four forms of DPP10. This antibody does not recognise other DPP family members.

We have a range of domain specific antibodies for this target. For a full list please see all DPP10 antibodies

Tested applications 
(see key)

WB

Abreviews 

Customer reviews (see key)

Read about Abreviews

Application notes 
(see key)

Recommended dilutions
WB: 1/1000 - 1/5000. Predicted molecular weight: 91 kDa. Recommended starting dilution 1/1000 for colourimetric substrates, 1/5000 for chemiluminescent substrates. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Type II membrane protein.

Research areas 

Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes >> Serine protease >> DPPs

Relevance 

A novel gene, DPP10, encodes a homolog of dipeptidyl peptidases (DPPs) that cleave terminal dipeptides from cytokines and chemokines, and it presents a potential new target for asthma therapy. The DPP10 protein shares features with members of the S9B family of DPP serine proteases, which includes DPP4, a widely expressed enzyme that plays a central role in chemokine processing as part of the innate immune system. The locus displays a complex pattern of transcript splicing, with eight alternate first exons; four of which localize within the LD block strongly associated with asthma.

This antibody recognises all four forms of DPP10.

Database links 

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Immunogen affinity purified

Storage buffer 

Preservative: 0.05% Sodium Azide
Constituents: 50% Glycerol, PBS, 0.5M Sodium chloride

Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

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