Overview

  • Product nameAnti-DPP2 antibody
    See all DPP2 primary antibodies
  • Description
    Rabbit polyclonal to DPP2
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human DPP2 (extracellular) conjugated to Keyhole Limpet Haemocyanin (KLH).

  • Positive control
    • Stomach

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.7
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab61824 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml.

Target

  • RelevanceDPP2 is a serine protease found most abundantly in the lysosome. There is also a non-lysosomal membrane-associated form of DPP2 reported in the rat brain (DPP-II-M), and a soluble form (DPP-II-S). First discovered as an enzyme involved in the terminal steps of protein degradation, and later as an enzyme involved in cell growth and quiescence, DPP2 cleaves N-terminal dipeptides and tripeptides from proteins. DPP2 has a preference for proline in the P1 position, and processes the tripeptides generated by DPP1 (which is unable to cleave if proline is in the P1 position). Some tumor cell lines express elevated DPP2 levels, and serum levels of DPP2 are elevated in some cancer patients, making DPP2 a potential tumor marker. DPP2 levels have been also been reported to be elevated in the cerebral spinal fluid from Parkinson’s patients.
  • Cellular localizationLysosome. Cytoplasmic vesicle. Secreted.
  • Database links
  • Alternative names
    • Dipeptidyl aminopeptidase II antibody
    • Dipeptidyl peptidase 7 antibody
    • Dipeptidyl peptidase II antibody
    • DPP II antibody
    • DPP2 antibody
    • DPP7 antibody
    • DPPII antibody
    • QPP antibody
    • Quiescent cell proline dipeptidase antibody
    • Weakly similar to LYSOSOMAL PRO X CARBOXYPEPTIDASE antibody
    see all

Anti-DPP2 antibody images

  • ab61824, at 10µg/ml, staining human DPP2 in stomach tissue by immunohistochemistry. Formalin-fixed paraffin-embedded tissue.

References for Anti-DPP2 antibody (ab61824)

ab61824 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"