Recombinant
RabMAb

Anti-DPP6 antibody [EPR15944] (ab191421)

Overview

  • Product name
    Anti-DPP6 antibody [EPR15944]
    See all DPP6 primary antibodies
  • Description
    Rabbit monoclonal [EPR15944] to DPP6
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    Recombinant fragment within Human DPP6 aa 400-550. The exact sequence is proprietary.
    Database link: P42658

  • Positive control
    • Human fetal brain lysate. Rat brain lysate.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.01% Sodium azide
    Constituents: 40% Glycerol, 0.05% BSA, 59% PBS
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Monoclonal
  • Clone number
    EPR15944
  • Isotype
    IgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab191421 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 115 kDa (predicted molecular weight: 98 kDa).

Target

  • Relevance
    DPP6 (DPPX, also known as potassium channel accelerating factor Dppx) is a Type-II serine proteinase of the clan SC. The clan SC proteinases have a catalytic triad of Ser-Asp-His, and like other Serine proteinases, the active site serine is in a Gly-Xaa-Ser-Xaa -Gly orientation. DPP6 has an Asp instead of Ser in the catalytic site. DPP6 is a member of a broader family of dipeptidyl peptidases including DPP4, FAP/Seprase, DPP2, DPP8, DPP9, DPP10, which have differing substrate specificity and tissue localizations. The surface-bound DPP6 is a homodimer, and cleavage of in the stalk region releases a shed form of DPP6. The shed is the form found in serum. DPP6 has been found in highest abundance in the brain, but also in the kidney, liver and lung.
  • Cellular localization
    Cell Membrane; single-pass type II membrane protein
  • Database links
  • Alternative names
    • Dipeptidyl aminopeptidase IV related protein antibody
    • Dipeptidyl aminopeptidase like protein 6 antibody
    • Dipeptidyl aminopeptidase related protein antibody
    • Dipeptidyl peptidase 6 antibody
    • Dipeptidyl peptidase IV like protein antibody
    • Dipeptidyl peptidase IV related protein antibody
    • Dipeptidylpeptidase 6 antibody
    • Dipeptidylpeptidase VI antibody
    • DPP VI antibody
    • DPPX antibody
    • VF2 antibody
    see all

Images

  • Anti-DPP6 antibody [EPR15944] (ab191421) at 1/1000 dilution + human fetal brain lysate at 20 µg

    Secondary
    Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

    Predicted band size: 98 kDa
    Observed band size: 115 kDa (why is the actual band size different from the predicted?)

  • Anti-DPP6 antibody [EPR15944] (ab191421) at 1/1000 dilution + rat brain lysate at 10 µg

    Secondary
    Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

    Predicted band size: 98 kDa
    Observed band size: 115 kDa (why is the actual band size different from the predicted?)

References

ab191421 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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