Overview

  • Product nameAnti-DPS1 antibody
  • Description
    Rabbit polyclonal to DPS1
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide: DDVIDDASSR RGKHTVNKIW GEKKAVLAGD LILSAASIAL ARIGNTTVIS , corresponding to internal sequence amino acids 180-229 of Human DPS1

  • Positive control
    • Fetal heart lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab80647 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 46 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay 1/12500.

Target

  • RelevanceDPS1 is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. It catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in this gene are a cause of coenzyme Q10 deficiency. There are three named isoforms.
  • Cellular localizationMitochondrial and Plasma membrane
  • Database links
  • Alternative names
    • Coenzyme Q1 homolog antibody
    • COQ1 antibody
    • Decaprenyl pyrophosphate synthetase subunit 1 antibody
    • DPS antibody
    • hDPS1 antibody
    • Polyprenyl pyrophosphate synthetase antibody
    • Prenyl (decaprenyl) diphosphate synthase, subunit 1 antibody
    • SPS antibody
    • TPRT antibody
    • TPT antibody
    • Trans prenyltransferase antibody
    see all

Anti-DPS1 antibody images

  • Anti-DPS1 antibody (ab80647) at 1 µg/ml + fetal heart lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 46 kDa
    Observed band size : 40 kDa (why is the actual band size different from the predicted?)

References for Anti-DPS1 antibody (ab80647)

ab80647 has not yet been referenced specifically in any publications.

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