Overview

  • Product nameAnti-DPY19L2 antibody
  • Description
    Rabbit polyclonal to DPY19L2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide derived from within residues: IGEFNNLPQE ELLQWIKYST TSDAVFAGAM PTMASIKLST LHPIVNHPHY, corresponding to amino acids 612 - 661 of Human DPY19L2 (NP_776173)

  • Positive control
    • Fetal heart lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab87596 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 87 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionRequired during spermatogenesis for sperm head elongation and acrosome formation.
  • Tissue specificityWidely expressed with high expression in testis. Not detectable in ejaculated sperm (at protein level).
  • Involvement in diseaseDefects in DPY19L2 are a cause of globozoospermia (GLOBZOOS) [MIM:102530]. An infertility disorder caused by spermatogenesis defects. The most prominent feature is the malformation of the acrosome. In the most severe cases the acrosome is totally absent. Globozoospermia is also characterized by abnormal nuclear shape as well as abnormal arrangement of the mitochondria of the spermatozoon. Note=Deletions in DPY19L2 are probably the major cause of GLOBZOOS.
  • Sequence similaritiesBelongs to the dpy-19 family.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • D19L2_HUMAN antibody
    • dpy 19 like 2 antibody
    • dpy 19 like 2 (C. elegans) antibody
    • Dpy 19 like protein 2 antibody
    • Dpy-19-like protein 2 antibody
    • dpy19 antibody
    • DPY19L2 antibody
    • FLJ32949 antibody
    • FLJ36166 antibody
    • Protein dpy 19 homolog 2 antibody
    • Protein dpy-19 homolog 2 antibody
    see all

Anti-DPY19L2 antibody images

  • Anti-DPY19L2 antibody (ab87596) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal heart lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 87 kDa

References for Anti-DPY19L2 antibody (ab87596)

ab87596 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"